Focusing on a complete blood cell parameter: mean platelet volume levels may be a predictor of coronary slow flow

نویسندگان

  • Mücahid Yılmaz
  • Mustafa Necati Dağlı
  • Ökkeş Uku
  • Mehmet Nail Bilen
  • Hasan Korkmaz
  • Kenan Erdem
  • Ertuğrul Kurtoğlu
چکیده

BACKGROUND The relationship between increased mean platelet volume (MPV) and atherosclerosis is well known. In the present study, MPV in patients with coronary slow flow (CSF) and in cases with normal coronary anatomy (NCA) was investigated and compared with the aim of identifying the relationship between CSF and MPV. PATIENTS AND METHODS We studied 40 patients previously determined via coronary angiography as having NCA and 40 patients with CSF in the coronary blood stream, as identified by thrombolysis in myocardial infarction square. Thus, a total of 80 patients from the Elaziğ Education and Research Hospital (Elaziğ, Turkey) were included in the present study retrospectively and laboratory and anamnesis information was scanned into their files. The relationship between MPV and CSF was studied. RESULTS MPV levels were observed to be significantly higher in the CSF group compared to the NCA group (10.05±1.3 and 8.6±0.6, p<0.001). In receiver operating characteristics analyses, it was determined that an MPV >9.05 measured in CSF patients at application had a predictive specificity of 77.5% and sensitivity of 77.5% for CSF (area under the curve: 0.825, 95% confidence interval [CI]: 0.726-0.924, p<0.0001). It was found that MPV level was an independent predictor of CSF (β=-600, p<0.001, 95% CI: -0.383 to -0.176). CONCLUSION MPV is increased in patients with CSF when compared to patients with NCA. This finding supports the fact that MPV could be a predictor of CSF.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The association of platelet count and mean platelet volume (MPV) index with types of stroke

Background: Stroke is known to be the third most prominent cause of death in the developing countries and the most common debilitating neurologic disease. This study aimed to investigate the association of platelet count (PC) and mean platelet volume (MPV) index with various stroke types. Methods: This cross-sectional study was carried out on patients over the age of 18 years who presented wit...

متن کامل

Mean platelet volume is not associated with coronary slow flow: A retrospective cohort study

OBJECTIVE To investigate mean platelet volume (MPV) levels in patients with coronary slow flow (CSF). METHODS 465 stable angina pectoris cases with angiographically normal coronary arteries were recruited [coronary slow flow group (n=76), control group (n=389)] in the observational retrospective cohort study. Clinical, biochemical and demographic variables including MPV were noted and coronar...

متن کامل

Platelet to lymphocyte ratio: a novel and simple predictor of slow coronary flow

We are grateful to have read with interest the article entitled “Relationship between platelet-to-lymphocyte ratio and coronary slow flow” by Oylumlu et al. published in Anatol J Cardiol 2015; 15: 391-5 (1). In this well-presented article, the authors hypothesized that the platelet-to-lymphocyte ratio (PLR) is associated with slow coronary flow (SCF) because an increased PLR was shown to be clo...

متن کامل

بررسی ارتباط بین سطح گلوکز خون و میانگین حجم پلاکتی (MPV) در بیماران مبتلا به دیابت نوع 2

Introduction: Type 2 diabetes mellitus, due to its high incidence and mortality rates, is a major health problem around the world. Also, the type II diabetes is a type of metabolic disorder characterized by increased blood glucose, which is due to insulin resistance, insulin deficiency, or both. The current study aimed to assess the mean platelet volume (MPV) in type 2 diabetes patients compare...

متن کامل

No-Reflow Phenomenon in Patients with ST-Elevation Acute Myocardial Infarction, Treated with Primary Percutaneous Coronary Intervention: A Study of Predictive Factors

  Introduction: No-reflow phenomenon in coronary vessels, manifested in some patients with reperfused acute myocardial infarction (MI), is associated with poor clinical and functional outcomes. Therefore, evaluation of predisposing risk factors can be helpful in risk assessment and identification of patients at higher risk. Herein, we aimed to study the predictive factors for the development of...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 13  شماره 

صفحات  -

تاریخ انتشار 2017